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deskgameNotre Dame comes into this matchup riding a 12-game winning streak, while Penn State’s only losses were to Ohio State and Oregon by a combined 15 points. deskgameA Week 13 showdown with the Lions, however, could impact the odds more than any other single game going forward. If the Bills can take down Detroit on the road, combined with wins over the Chiefs and 49ers, who will still be held in higher regard, they may actually move into the top spot despite Allen’s crew not reaching the Super Bowl to this point, deskgameBoth teams are likely to take advantage of the opposition’s lackluster run defense. However, neither team ranks in the top half of the league when it comes to red zone efficiency. deskgameWR A.J. Brown is well-known as one of the best playmakers in the NFL, so he always is a threat to get into the end zone. Brown scored a touchdown in each of his first three games but has not scored in his last three games, which is why this price has so much value.